Antiviral Powder Trifluridine CAS 70-00-8 For Anti-fection

Quick details of Trifluridine powder
Product Name:    Trifluridine
Synonyms:    2,4(1h,3h)-pyrimidinedione,1-(2-deoxy-beta-d-ribofuranosyl)-5-(trifluorometh;Trifluridine (Viroptic);VIROPTIC; TRIFLUOROTHYMIDINE;Triflurdine (Viroptic);2'-deoxy-5-(trifluoromethyl)-uridin;5-(trifluoromethyl)deoxyuridine;5-trifluoro-2'-deoxythymidine;alpha,alpha,alpha-trifluoro-thymidin
CAS:    70-00-8
MF:    C10H11F3N2O5
MW:    296.2
EINECS:    200-722-8
Product Categories:    PARSOL;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Pharmaceutical Raw Materials;Pyrimidine series;API intermediates;Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides
Mol File:    70-00-8.mol

Trifluridine (trifluorothymidine, TFT), a fluorinated pyrimidine nucleoside, is an anti-herpesvirus agent and an antitumor antimetabolite agent. It is an analog of thymidine which inhibits thymidylate synthase possesses antiviral and anticancer activity. After phosphorylation by thymidine kinase, it is incorporated into DNA where it induces DNA-damage and interferes with repair enzymes. Enhances frame shift insertion and deletion in CRISPR genome editing in pluripotent stem cells.

Trifluridine CAS 70-00-8 of Chemical Properties
Melting point     190-193 °C (lit.)
density     1.4365 (estimate)
refractive index     50 ° (C=1, H2O)
storage temp.     2-8°C
solubility     Soluble in DMSO (up to 25 mg/ml) or in Water (up to 14 mg/ml)
form     solid
pka    pKa 7.85 (Uncertain)
color     Off-white
Merck     14,9687
Stability:    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
CAS DataBase Reference    70-00-8(CAS DataBase Reference)

Our Advantage:

1. high quality with competitive price
2. High quality standard: BP/USP/EP Enterprise standard
3. All purity customized
4. Fast and safe delivery
5. We have reliable forwarder who can help us deliver our goods more fast and safe.
6. We have stock and can deliver small quantity at once.

Function and Application of Trifluridine CAS 70-00-8
1. Trifluridine is used as anti-herpesvirus antiviral agent in ophthalmie preparations.
2. Trifluridine is also used as an anti-cancer nucleoside, mainly for the treatment of colorectal cancer, especially for the early treatment of colon cancer patients. Trimethoprim interacts directly with the DNA of the cancer, preventing the DNA from functioning properly.
3. Trifluridine ia a broad-spectrum antiviral drug, inhibits herpes simplex virus, adenovirus, herpes zoster virus, HSV-I, HSV-II, CMV, varicella virus and some adenoviruses.
4. Trafluridine is mainly used for herpes virus causing conjunctivitis, keratitis and other herpetic eye diseases. It is more effective than iodoside. It is commonly used in patients who have failed to respond to cytarabine treatment.

Product  Description：

Artemisinin and its semi-synthetic derivatives are a group of drugs used against Plasmodium falciparum malaria. Artemisinin is isolated from the plant Artemisia annua, sweet wormwood, a herb employed in Chinese traditional medicine. Chemically, artemisinin is a sesquiterpene lactonecontaining an unusual peroxide bridge. This peroxide is believed to be responsible for the drug's mechanism of action.

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Company Profile：

Wuhan Han Sheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.

We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on.

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Exhibitions:

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Products & Packaging：

Our products are used for pharmaceuticals, pesticides, synthetic dyes, organic chemicals, inorganic chemicals, coatings, spices and essence, cosmetics and toilet products, soaps and synthetic detergents, surfactants, printing inks and their auxiliaries, adhesives, photosensitive materials, magnetic materials, catalysts, reagents, water treatment agents and polymer flocculants, papermaking auxiliaries, leather auxiliaries, synthetic materials auxiliaries, textile printing and dyeing agents and finishing agents, food additives Feed additives, animal drugs, etc.

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About  Us 

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Shipment & Payment：

*small quantity: By Fedex, DHL, HKPOST, UPS, TNT or As customers’ requirement

*Bulk order: By air or sea

*Delivery: within 3 days for samples and 10 days for bulk order

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Our Markets: 

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FAQ

1. Are you a trade company or factory

We are a factory with our own trading company.

2. How do you control the quality

Our factory is equipped with professional technicians to inspect the quality around production lines. The inspection test would be made every 2 hours to ensure the production conform to quality standard. We also accept BV, SGS, or any third pary inspection.

3. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

4. Where is your factory located How can I visit the factory

Our factory located in Hebei, China

5. Can I get some samples

Yes, we can supply sample with free, but the shipping cost be paid by our customers.

6. How to start orders or make payments

Proforma Invoice will be issued first after confirmation of order, enclosed our bank information. Payment could be done by T/T or .

7. How to confirm the product quality before placing order

You can get free samples for some products. You only need to pay the shipping cost or arrange a courier to us and take the samples.

8. How do you treat quality complaint

First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.