Wuhan Han Sheng New Material Technology Co.，Ltd(expird)
Free supplier
- Free
supplier - 3rd
years
Free supplier
Business Type:Trading Company
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
CAS NO.656247-17-5
| Molecular Formula | C31H33N5O4 |
| Molar Mass | 539.64 |
| Density | 1.284±0.06 g/cm3(Predicted) |
| Melting Point | >237oC (dec.) |
| Boling Point | 742.2±60.0 °C(Predicted) |
| Solubility | DMSO 6 mg/mL Water <1 mg/mL Ethanol 3 mg/mL |
| Appearance | Form Yellow solid, color Light Yellow to Light Green |
| Color | Light Yellow to Light Green |
| pKa | 11.06±0.20(Predicted) |
| Storage Condition | Refrigerator |
| Use | BIBF1120 is a potent kinase inhibitor found to affect VEGF, PDGF, and FGF receptors. |
| In vitro study | BIBF1120 has little inhibitory effect on tyrosine kinase receptors such as EGFR, HER2, InsR, IGF1R or cell cycle kinases CDK1, CDK2 and CDK4, and IC50 is greater than 1x10 |
| In vivo study | Treatment of 100mg BIBF 1120 per kg of mouse body weight in Fadu xenografts showed a 76% reduction in tumor vessel density. BIBF1120 also had significant inhibitory effects on transplanted tumor models Caki-1, HT-29, SKOV-3, Calu6 and PAC-120. BIBF 1120 has been used to treat a variety of cancers including non-small cell lung cancer, prostate cancer, ovarian cancer, and colorectal cancer. BIBF 1120 is currently in Phase II clinical trials. |
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Wuhan Han Sheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.
We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on.
Our products are used for pharmaceuticals, pesticides, synthetic dyes, organic chemicals, inorganic chemicals, coatings, spices and essence, cosmetics and toilet products, soaps and synthetic detergents, surfactants, printing inks and their auxiliaries, adhesives, photosensitive materials, magnetic materials, catalysts, reagents, water treatment agents and polymer flocculants, papermaking auxiliaries, leather auxiliaries, synthetic materials auxiliaries, textile printing and dyeing agents and finishing agents, food additives Feed additives, animal drugs, etc.
About Us
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*small quantity: By Fedex, DHL, HKPOST, UPS, TNT or As customers’ requirement
*Bulk order: By air or sea
*Delivery: within 3 days for samples and 10 days for bulk order