Wuhan Han Sheng New Material Technology Co.，Ltd(expird)
Free supplier
- Free
supplier - 3rd
years
Free supplier
Business Type:Trading Company
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
CAS NO.608512-97-6
| Molecular Formula | C13H8N4OS |
| Molar Mass | 268.29 |
| Density | 1.604±0.06 g/cm3(Predicted) |
| Boling Point | 674.6±55.0 °C(Predicted) |
| Solubility | Soluble in DMSO |
| Appearance | Orange to orange brown solid |
| Color | yellow to orange-brown |
| pKa | 10.20±0.20(Predicted) |
| Storage Condition | -20°C |
| Stability | Stable for 2 years from date of purchsae as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
| Use | PKR-IN-C16 are specific protein kinase (PKR) inhibitors. PKR-IN-C16 can inhibit the autophosphorylation of PKR, and the translation blockade induced by PKR in primary neuron cell culture can be relieved by PKR-IN-C16. C16, also known as GW-506033X or PKR Inhibitor. C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM. GW-506033X protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress. PKR inhibitor C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a neuroinflammatory component. PKR inhibitor C16 binds efficiently with human microtubule affinity-regulating kinase 4. |
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Wuhan Han Sheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.
We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on.
Our products are used for pharmaceuticals, pesticides, synthetic dyes, organic chemicals, inorganic chemicals, coatings, spices and essence, cosmetics and toilet products, soaps and synthetic detergents, surfactants, printing inks and their auxiliaries, adhesives, photosensitive materials, magnetic materials, catalysts, reagents, water treatment agents and polymer flocculants, papermaking auxiliaries, leather auxiliaries, synthetic materials auxiliaries, textile printing and dyeing agents and finishing agents, food additives Feed additives, animal drugs, etc.
About Us
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*small quantity: By Fedex, DHL, HKPOST, UPS, TNT or As customers’ requirement
*Bulk order: By air or sea
*Delivery: within 3 days for samples and 10 days for bulk order