Wuhan Han Sheng New Material Technology Co.，Ltd(expird)
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CAS NO.53179-11-6
| Molecular Formula | C29H33ClN2O2 |
| Molar Mass | 477.04 |
| Density | 1.187±0.06 g/cm3(Predicted) |
| Boling Point | 647.2±55.0 °C(Predicted) |
| pKa | pKa 8.66(H2O) (Uncertain) |
| Physical and Chemical Properties | Chemical properties of loperamide hydrochloride: C29H33ClN2O2 HCl. [34552-83-5]. Crystallization from isopropanol, melting point 222-223 °c. UV maximum absorption (0.1mol/L hydrochloric acid/2-propanol, 10ml/90 ml):253,259,265,273nm (φ532, 648,581,233). Solubility (g/100ml): Water (pH 1.7)0.14, citrate-phosphate (pH 6.1)0.008, citrate-phosphate (pH 7.9)<0.001, methanol 28.6, ethanol 5.37, 2-chemical book propanol 1.11, dichloromethane 35.1, acetone 0.20, ethyl acetate 0.035, diethyl ether <0.001, hexane <0.001, toluene 0.001, dimethylformamide 10.3, tetrahydrofuran 0.32, 4-methyl-2-pentanone 0.020, propylene glycol 5.64, polyethylene glycol 4001.40, dimethyl sulfoxide 20.5, 2-butanone 0.18. PKA 8.66. In the physiological pH range of a few insoluble in water (0.002%). Stable, under normal conditions can be stored for several years. Non-hygroscopic, not sensitive to light. Acute toxicity. Mice (mg/kg):75 subcutaneous injection; 105 oral. Acute toxicity LD50 rats (mg/kg):185 oral. |
| Use | The use of a strong long-acting anti-diarrhea drugs. Its chemical structure is similar to haloperidol and pethidine, but the therapeutic dose has no effect on the central nervous system. It is suitable for acute Diarrhea and chronic Diarrhea caused by various causes, such as ulcerative colitis, nonspecific colitis, irritable bowel syndrome and the treatment of chronic Diarrhea caused by partial gastrectomy and hyperthyroidism. |
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Wuhan Han Sheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.
We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on.
Our products are used for pharmaceuticals, pesticides, synthetic dyes, organic chemicals, inorganic chemicals, coatings, spices and essence, cosmetics and toilet products, soaps and synthetic detergents, surfactants, printing inks and their auxiliaries, adhesives, photosensitive materials, magnetic materials, catalysts, reagents, water treatment agents and polymer flocculants, papermaking auxiliaries, leather auxiliaries, synthetic materials auxiliaries, textile printing and dyeing agents and finishing agents, food additives Feed additives, animal drugs, etc.
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