- Product Details
Keywords
- Sorafenib CAS NO.284461-73-0
- 284461-73-0
- 608-209-4
Quick Details
- ProName: Sorafenib CAS NO.284461-73-0
- CasNo: 284461-73-0
- Molecular Formula: C21H16ClF3N4O3
- Appearance: White to Off-White Solid
- Application: Pharmaceuticals, pesticides, synthetic...
- DeliveryTime: 3-10 days
- PackAge: 1kg/Alu bag, 25kgs/Drum
- Port: Wuhan
- ProductionCapacity: 100 Metric Ton/Month
- Purity: 99%
- Storage: Dry and Cool Place and Keep Away From ...
- Transportation: *small quantity: By Fedex, DHL, HKPOST...
- LimitNum: 10 Kilogram
Superiority
Our Advantage:
- high quality with competitive price
- High quality standard: BP/USP/EP Enterprise standard
- All purity customized
- Fast and safe delivery
- We have reliable forwarder who can help us deliver our goods more fast and safe.
- We have stock and can deliver small quantity at once.
Details
Product Description:
Product Name: | Sorafenib |
CAS: | 284461-73-0 |
MF: | C21H16ClF3N4O3 |
MW: | 464.82 |
EINECS: | 608-209-4 |
Melting point | 202-204°C |
Boiling point | 523.3±50.0 °C(Predicted) |
density | 1.454±0.06 g/cm3(Predicted) |
vapor pressure | 0Pa at 25℃ |
storage temp. | Sealed in dry,Store in freezer, under -20°C |
solubility | Chloroform (Slightly), DMSO (Slightly) |
pka | 12.89±0.70(Predicted) |
form | White to off-white solid. |
color | White to Off-White |
Water Solubility | 100μg/L at 20℃ |
LogP | 3.3 at 25℃ |
Uses | Sorafenib, an orally active potent multi-kinases inhibitor,was approved in the U.S. for the treatment of advanced renalcell carcinoma. The drug targets both tumor cell proliferationand tumor angiogenesis kinases that include RAF,VEGFR-2, VEGFR-3, PDGFR-b, KIT and FLT-3. Sorafenibis being jointly developed by Bayer and Onyx in phase IIItrials as a single agent for the treatment of advanced hepato-cellular carcinoma and in combination with carboplatin andpaclitaxel in patients with advanced metastatic melanoma.Phase II trials in combination with doxorubicin for thetreatment of advanced hepatocellular carcinoma are alsounder investigation. Additional phase II trials are ongoingfor non-small cell lung cancer (NSCLC) and in postmenopausalwomen with estrogen receptor and/or progesteronereceptor-positive metastatic breast cancer. In addition, theNational Cancer Institute (NCI) is evaluating the compoundboth as a single therapy agent and in combination with otheroncology agents in phase II trials for several cancer indications. |
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Company Profile:
Wuhan Han Sheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.
We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on.
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Exhibitions:
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Products & Packaging:
Our products are used for pharmaceuticals, pesticides, synthetic dyes, organic chemicals, inorganic chemicals, coatings, spices and essence, cosmetics and toilet products, soaps and synthetic detergents, surfactants, printing inks and their auxiliaries, adhesives, photosensitive materials, magnetic materials, catalysts, reagents, water treatment agents and polymer flocculants, papermaking auxiliaries, leather auxiliaries, synthetic materials auxiliaries, textile printing and dyeing agents and finishing agents, food additives Feed additives, animal drugs, etc.
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About Us
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Shipment & Payment:
*small quantity: By Fedex, DHL, HKPOST, UPS, TNT or As customers’ requirement
*Bulk order: By air or sea
*Delivery: within 3 days for samples and 10 days for bulk order
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Our Markets:
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FAQ
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Are you a trade company or factory
We are a factory with our own trading company.
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How do you control the quality
Our factory is equipped with professional technicians to inspect the quality around production lines. The inspection test would be made every 2 hours to ensure the production conform to quality standard. We also accept BV, SGS, or any third pary inspection.
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How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
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Where is your factory located How can I visit the factory
Our factory located in Hebei, China
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Can I get some samples
Yes, we can supply sample with free, but the shipping cost be paid by our customers.
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How to start orders or make payments
Proforma Invoice will be issued first after confirmation of order, enclosed our bank information. Payment could be done by T/T or .
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How to confirm the product quality before placing order
You can get free samples for some products. You only need to pay the shipping cost or arrange a courier to us and take the samples.
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How do you treat quality complaint