Details
Product Description：
Linezolid reached the US market for the treatment of patients with infections caused by serious Gram-positive pathogens, particularly skin and soft tissue infections, communityacquired pneumonia and vancomycin-resistant enterococcal infections. Linezolid is the (S)-enantiomer of an oxazolidin-2-one synthesized in a multistep process from 3,4- difluoronitrobenzene, the key step being the cyclization of a carbamate, using a chiral epoxyester, into an enantiomerically pure oxazolidin-2-one. Linezolid can be considered as the first of a new class of antibacterial agents known as oxazolidinones, its mechanism of action being related to the inhibition of early ribosomal protein synthesis without directly inhibiting DNA or RNA synthesis. In vitro studies demonstrated that linezolid was effective, at potency levels similar to vancomycin, against staphylococcal, streptococcal and pneumococcal infections (MIC values in the range of 0.5 to 2 μg/ml), enterococcal species including VRE and VSE (MIC values about 4 μg/ml), but also other vancomycin-resistant bacteria. Linezolid is rapidly absorbed orally, its bioavailability is nearly complete at 250 mg dose giving a Cmax to MIC ratio sufficient to have pathogenic strain eradication in the clinical setting. It is considered that this new promising agent may offer new options for therapy of multi-drug infections.
| Product Name |
Linezolid |
| EINECS |
605-416-1 |
| Melting point |
176-1780C |
| Boiling point |
585.5±50.0 °C(Predicted) |
| Density |
1.302±0.06 g/cm3(Predicted) |
| Solubility |
DMSO: >20mg/mL |
| Pka |
0.12±0.10(Predicted) |
| Form |
powder |
| Color |
Yellow to Pale Orange Liquid |
| HS Code |
29419000 |
| Alpha |
D20 -9° (c = 0.919 in chloroform) |
| InChIKey |
TYZROVQLWOKYKF-ZDUSSCGKSA-N |
| BCS Class |
4 |
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Company Profile：
Wuhan Han Sheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.
We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on.
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Exhibitions:
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Products & Packaging：
Our products are used for pharmaceuticals, pesticides, synthetic dyes, organic chemicals, inorganic chemicals, coatings, spices and essence, cosmetics and toilet products, soaps and synthetic detergents, surfactants, printing inks and their auxiliaries, adhesives, photosensitive materials, magnetic materials, catalysts, reagents, water treatment agents and polymer flocculants, papermaking auxiliaries, leather auxiliaries, synthetic materials auxiliaries, textile printing and dyeing agents and finishing agents, food additives Feed additives, animal drugs, etc.
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About Us
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Shipment & Payment：
*small quantity: By Fedex, DHL, HKPOST, UPS, TNT or As customers’ requirement
*Bulk order: By air or sea
*Delivery: within 3 days for samples and 10 days for bulk order
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Our Markets:
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FAQ
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Are you a trade company or factory
We are a factory with our own trading company.
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How do you control the quality
Our factory is equipped with professional technicians to inspect the quality around production lines. The inspection test would be made every 2 hours to ensure the production conform to quality standard. We also accept BV, SGS, or any third pary inspection.
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How long is lead time
We deliver goods within 3 days for small order, 7-10 days for bulk order.
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Where is your factory located How can I visit the factory
Our factory located in Hebei, China
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Can I get some samples
Yes, we can supply sample with free, but the shipping cost be paid by our customers.
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How to start orders or make payments
Proforma Invoice will be issued first after confirmation of order, enclosed our bank information. Payment could be done by T/T or .
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How to confirm the product quality before placing order
You can get free samples for some products. You only need to pay the shipping cost or arrange a courier to us and take the samples.
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How do you treat quality complaint
First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
China (Mainland)