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CAS NO.923950-08-7
Dulaglutide is a once-weekly GLP-1R agonist approved for the treatment of T2DM in 2014. This drug is an incretin-related drugs. It is a recombinant DNA-produced polypeptide analog of GLP-1(7-37) that is covalently linked to each Fc arm of human immunoglobulin G4 (IgG4). The structure of dulaglutide confers improved solubility, reduced immunogenicity, and reduced rate of renal clearance. The peptide can be used either as a stand-alone therapy or in combination with other medicines for T2DM, in particular metformin and insulin. Dulaglutide has been studied in comparison with other anti-diabetic drugs in multiple trials. In the AWARD-6 trial, once-weekly 1.5 mg dulaglutide showed a comparable efficacy to daily 1.8 mg liraglutide in reducing HbA1c levels, but was less efficacious than liraglutide with respect to weight loss[1].
Product Name | Dulaglutide |
Melting point | >300° |
Boiling point | 1055.2±65.0 °C(Predicted) |
Density | 1.42±0.1 g/cm3(Predicted) |
Solubility | PBS (pH 7.2): 10 mg/ml |
Pka | 3.07±0.10(Predicted) |
Form | Solid |
Color | White |
Odor | Odor of the solvent |
Mol File | 923950-08-7.mol |
MW | 3751.202 |
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Wuhan Han Sheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.
We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on.
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