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CAS NO.55-22-1
Isonicotinic acid is a metabolite of isoniazid. It is an isomer of nicotinic acid. The chronic toxicity of isonicotinic acid is slightly higher than that of isonicotinic acid hydrazide ( INH ) .
Isonicotinic acid is a moderately basic compound (based on its pKa). Isonicotinic acid is an organic compound with a carboxyl group on a pyridine ring. The carboxyl group for isonicotinic acid is on the 4-position instead of the 3-position for nicotinic acid. It is an isomer of nicotinic acid. Isonicotinic acid is a metabolite of isoniazid.
Isonicotinic acid considered to be inactive isomer of nicotinic acid. Isonicotinic acid is a metabolite of pyridine-4-carboxy hydrazide (isonicotinyl hydrazide; isoniazid) a front-line weapon in the battle against tuberculosis. Isonicotinic acid and its derivatives are used in manufacturing pharmaceuticals and agrochemicals.
Used in the biological study of differentiation induced by nicotinic acid, nicotinamide and isonicotinic acid in human leukemia cell lines
Product Name: | Isonicotinic acid |
CAS: | 55-22-1 |
MF: | C6H5NO2 |
MW: | 123.11 |
EINECS: | 200-228-2 |
Melting point | ≥300 °C (lit.) |
Boiling point | 260 °C (15 mmHg) |
density | 1,47g/cm |
refractive index | 1.5423 (estimate) |
Fp | 260°C/15mm |
storage temp. | no restrictions. |
solubility | 6g/l |
pka | 4.96(at 25℃) |
form | powder |
color | yellow to tan |
PH | 3-4 (6g/l, H2O, 20℃)(saturated solution) |
Water Solubility | 5.2 g/L (20 ºC) |
Merck | 14,5187 |
BRN | 109599 |
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