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Country: China (Mainland)
Business Type:Trading Company
CAS NO.20311-51-7
Molecular Formula | C45H73NO15 |
Molar Mass | 868.06 |
Density | 1.38 |
Melting Point | 301 °C |
Specific Rotation(α) | (MeOH)-105;(Py)-102 |
Solubility | Soluble in methanol, hot water, slightly soluble in ethyl acetate, insoluble in petroleum ether |
Appearance | White crystalline powder |
Color | Light Beige |
pKa | 12+-.0.70(Predicted) |
Storage Condition | Refrigerator |
Refractive Index | 1.618 |
MDL | MFCD30207844 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, comes from Forst, a Solanum aviculare of Australian eggplant. Fruit. |
In vitro study | Solamargine (15 μg/ml; 72 hours) predominantly stimulates the cells of the G2/M phase to apoptosis. Solamargine (72 hours) dramatically inhibits the proliferation of SMMC-7721 and HepG2 cells in a dose- and time-dependent manner. The IC 50 s are 9.21 and 19.88 μg/ml, respectively. Cell Viability Assay Cell Line: SMMC-7721cells Concentration: 15 μg/ml Incubation Time: 72 hours Result: Displayed a significant increase of sub-G1. |
In vivo study | Solamargine (10 mg/kg; intragastric administration; once daily for 8 days) exhibits an antitumor effect and promotes the apoptosis of GC in vivo. Animal Model: Female specific pathogen-free BALB/c nude mice weighing 18-20 g (6-8-weeks-old) Dosage: 10 mg/kg Administration: Intragastric administration; once daily for 8 days Result: Tumor growth was significantly inhibited . |
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Wuhan Han Sheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.
We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on.
Our products are used for pharmaceuticals, pesticides, synthetic dyes, organic chemicals, inorganic chemicals, coatings, spices and essence, cosmetics and toilet products, soaps and synthetic detergents, surfactants, printing inks and their auxiliaries, adhesives, photosensitive materials, magnetic materials, catalysts, reagents, water treatment agents and polymer flocculants, papermaking auxiliaries, leather auxiliaries, synthetic materials auxiliaries, textile printing and dyeing agents and finishing agents, food additives Feed additives, animal drugs, etc.
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