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Country: China (Mainland)
Business Type:Trading Company
CAS NO.13647-35-3
Product Name: | Trilostane |
CAS: | 13647-35-3 |
MF: | C20H27NO3 |
MW: | 329.43 |
EINECS: | 237-133-0 |
Melting point | 264 °C |
alpha | D25 +137.4° (c = 1 in pyridine) |
Boiling point | 467.02°C (rough estimate) |
density | 1.1213 (rough estimate) |
refractive index | 1.5614 (estimate) |
storage temp. | 2-8°C |
solubility | DMSO: ≥17mg/mL |
form | powder |
pka | 8.57±0.70(Predicted) |
color | white to tan |
Usage:
Trilostane was withdrawn from the United States market in April 1994. However, it was approved in 2008 for the treatment of Cushing's disease (hyperandrenocorticism) in dogs.
It is also the first drug approved to treat both pituitary-and adrenal-dependent Cushing's in dogs.
1. has kidney or liver disease.
2. takes certain medications used to treat heart disease.
3. pregnant.
4. taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
5. had an allergic reaction to this or any other medicine.
An inhibitor of steroid biosynthesis. Used as an adrenocortical suppressant. Used in the treatment of breast cancer.
antifungal, inhibits mitosis in metaphase
Trilostane has been used to evaluate its capability to regulate the sex-dependent differences in the lipopolysaccharide (LPS)-induced inflammatory responses of astrocytes.
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Wuhan Han Sheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.
We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on.
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