Wuhan Han Sheng New Material Technology Co.，Ltd(expird)
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- Free
supplier - 3rd
years
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Business Type:Trading Company
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Country: 
China (Mainland)
Business Type:Trading Company
CAS NO.1229705-06-9
| Molecular Formula | C31H29Cl2F2N3O4 |
| Molar Mass | 616.48 |
| Density | 1.40±0.1 g/cm3(Predicted) |
| Melting Point | >261° (dec.) |
| Boling Point | 737.3±60.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Appearance | Form Solid, color White to Off-White |
| Color | White to Off-White |
| pKa | 4.11±0.10(Predicted) |
| Storage Condition | -20°C Freezer |
| Physical and Chemical Properties | Bioactive Idasanutlin (RG-7388) is a potent selective p53-MDM2 inhibitor with an IC50 of 6 nM. Its in vitro binding force, potency and selectivity in cells have been greatly improved. |
| Use | Bioactive Idasanutlin (RG-7388) is a potent selective p53-MDM2 inhibitor with an IC50 of 6 nM. Its in vitro binding force, potency and selectivity in cells have been greatly improved. |
| In vitro study | In cancer cells expressing wild-type p53, Idasanutlin inhibited cell proliferation with an IC50 of 30 nM and dose-dependently induced p53 stabilization, cell cycle arrest, and apoptosis. |
| In vivo study | In the mouse SJSA human osteosarcoma xenograft model, Idasanutlin (25 mg/kg p.o.) inhibited tumor growth and allowed regression. In the SJSA xenograft model, Idasanutlin induces apoptosis and is anti-proliferative. |
Wuhan Han Sheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.
We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on.
Our products are used for pharmaceuticals, pesticides, synthetic dyes, organic chemicals, inorganic chemicals, coatings, spices and essence, cosmetics and toilet products, soaps and synthetic detergents, surfactants, printing inks and their auxiliaries, adhesives, photosensitive materials, magnetic materials, catalysts, reagents, water treatment agents and polymer flocculants, papermaking auxiliaries, leather auxiliaries, synthetic materials auxiliaries, textile printing and dyeing agents and finishing agents, food additives Feed additives, animal drugs, etc.
About Us
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*small quantity: By Fedex, DHL, HKPOST, UPS, TNT or As customers’ requirement
*Bulk order: By air or sea
*Delivery: within 3 days for samples and 10 days for bulk order