Business Type:Trading Company
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Country: China (Mainland)
Business Type:Trading Company
CAS NO.1026680-07-8
Molecular Formula | C13H20N2O4 |
Molar Mass | 268.3089 |
Melting Point | >214°C (dec.) |
Solubility | DMSO (Very Slightly, Heated), Methanol (Very Slightly, Heated) |
Appearance | Solid |
Color | White |
Storage Condition | Amber Vial, -20°C Freezer, Under inert atmosphere |
In vitro study | LB-100 can effectively inhibit the growth of BxPc-3 and Panc-1 cells, IC50 values were 2.3 μm and 1.7 μm. After BxPc-3, Panc-1 and SW1990 cells were treated with LB-100, the activity of PP2A decreased by 30-50%. LB-100 increased the intracellular doxorubicin concentration (about 2.5 times that of the control group) and made the tumor cells more sensitive to doxorubicin cytotoxicity. LB-100 increases VEGF secretion, thereby enhancing hif-1α-VEGF mediated angiogenesis. |
In vivo study | In a mouse pancreatic cancer xenograft model, LB-100 (2 mg/kg, I. P.) improved the efficacy of the chemotherapeutic drug doxorubicin. LB-100 increased tumor microvessel density and tumor surface blood flow velocity. |
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Wuhan Han Sheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.
We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on.
Our products are used for pharmaceuticals, pesticides, synthetic dyes, organic chemicals, inorganic chemicals, coatings, spices and essence, cosmetics and toilet products, soaps and synthetic detergents, surfactants, printing inks and their auxiliaries, adhesives, photosensitive materials, magnetic materials, catalysts, reagents, water treatment agents and polymer flocculants, papermaking auxiliaries, leather auxiliaries, synthetic materials auxiliaries, textile printing and dyeing agents and finishing agents, food additives Feed additives, animal drugs, etc.
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