Our Advantage:

1. High quality with competitive price
2. High quality standard: BP/USP/EP Enterprise standard
3. All purity customized
4. Fast and safe delivery
5. We have reliable forwarder who can help us deliver our goods more fast and safe.
6. We have stock and can deliver small quantity at once.

Product  Description：

Promethazine (PM) ((RS)-N, N-dimethyl-1-(10H-phenothiazine-10-yl)propan-2-amine hydrochloride) is a phenothiazine derivative. It is a first-generation H1 receptor antagonist, antihistamine, and antiemetic medication and can also have strong sedative effects^[1]. Promethazine affects ligand gated ion channels such as purinergic P2 or cholinergic ACh receptors and voltage dependent ion channels such as sodium, calcium, or potassium channels.

Beside, these effects, promethazine also inhibit the brain NaþKþ-ATPase and the mitochondrial permeability transition pore. Since its first introduction in 1946, it has been used for prevention and treatment of nausea and vomiting caused by narcotic therapy, migraine episodes, cancer chemotherapy, and so forth.^[2] Meanwhile, it has become apparent that this drug interacts with many different receptors. It works by changing the actions of chemicals in brain and as an antihistamine^[2]. It is used to treat allergic symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes, also to prevent motion sickness, and treat to nausea and vomiting pain after surgery and as a sedative or sleep aid, especially for oncologic patients. However, second-generation oral antihistamines are the preferred first-line treatment option for allergic rhinitis and urticarial, although topical first-generation antihistamines are still prescribed by general healthcare practitioner and pharmacists too easily, without taking into account possible side effects as a first line treatment for several dermatological problems^[3–8].

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Company Profile：

Wuhan Han Sheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.

We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on.

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Exhibitions:

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Products & Packaging：

Our products are used for pharmaceuticals, pesticides, synthetic dyes, organic chemicals, inorganic chemicals, coatings, spices and essence, cosmetics and toilet products, soaps and synthetic detergents, surfactants, printing inks and their auxiliaries, adhesives, photosensitive materials, magnetic materials, catalysts, reagents, water treatment agents and polymer flocculants, papermaking auxiliaries, leather auxiliaries, synthetic materials auxiliaries, textile printing and dyeing agents and finishing agents, food additives Feed additives, animal drugs, etc.

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About  Us 

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Shipment & Payment：

*small quantity: By Fedex, DHL, HKPOST, UPS, TNT or As customers’ requirement

*Bulk order: By air or sea

*Delivery: within 3 days for samples and 10 days for bulk order

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Our Markets: 

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FAQ

1. Are you a trade company or factory

We are a factory with our own trading company.

2. How do you control the quality

Our factory is equipped with professional technicians to inspect the quality around production lines. The inspection test would be made every 2 hours to ensure the production conform to quality standard. We also accept BV, SGS, or any third pary inspection.

3. How long is lead time

We deliver goods within 3 days for small order, 7-10 days for bulk order.

4. Where is your factory located How can I visit the factory

Our factory located in Hebei, China

5. Can I get some samples

Yes, we can supply sample with free, but the shipping cost be paid by our customers.

6. How to start orders or make payments

Proforma Invoice will be issued first after confirmation of order, enclosed our bank information. Payment could be done by T/T or .

7. How to confirm the product quality before placing order

You can get free samples for some products. You only need to pay the shipping cost or arrange a courier to us and take the samples.

8. How do you treat quality complaint

First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.